The extracted and dried green micro algae by using solvents Acetone, Ethanol and Chloroform assy is tested to know its efficiency against four bacterial strains under the cultured conditions by adopting the standard agar disc diffusion technique. These agar plates are incubated at 37°C for 24 hour duration with four test bacterial strains in 10ml each of Acetone, Ethanol and Chloroform with extracted green micro algae. These extracts exhibits optimal effects on inhibitory efficiency. The observed highest inhibition zone zone is 13mm in Chlorella Vulgaris extracted with Ethanol against klebsilla sp.,. The performed preliminary phytochemical analysis of this dried algal sample as per the Harborne methode reveals that this assay withhold some of the valuable bioactive compounds. It is flavanoids, tannin, phenolic compounds, terpenes, cardiac glycosides, saponins and carbohydrates. The substantial evidence of the presence of these seven bioactive compounds revealed that Chlorella vulgar is having major role as a useful precursor to obtain various bioactive compounds. This algae species exhibits its maximum inhibition property with Klebsilla sp. This enables to discover some of new derivatives with more investigation about its feasibility of finding new drugs by the application of procedures adopted in drug discovery and designing. The drugs derived from these algae species will find some specific application to curtile the growth of the bacteria which results the control of Vector infections without any side effects in a more specific manner.